/* ==========================================================================
   RegenBrief — Provided by DYPHI Functional Longevity Center
   ========================================================================== */

/* Pretendard Variable — 한국어 UI/레이블용 (가독성 최상위 모던 고딕) */
@import url('https://cdn.jsdelivr.net/npm/pretendard@1.3.9/dist/web/variable/pretendardvariable.min.css');

/* Noto Serif KR — 본문·헤딩용 (한국어 장문 가독성, 권위 있는 학술 세리프) */
/* JetBrains Mono — 코드·날짜·레이블 */
@import url('https://fonts.googleapis.com/css2?family=Noto+Serif+KR:wght@400;500;600;700&family=JetBrains+Mono:wght@400;500&display=swap');

:root {
  /* Palette — 묵직한 잉크 베이스, 절제된 크림 */
  --ink: #111114;
  --ink-soft: #3a3a3f;
  --ink-mute: #6e6e74;
  --paper: #f7f5ef;            /* 부드러운 크림, 무광 종이 */
  --paper-warm: #efece2;
  --paper-deep: #e6e2d4;
  --rule: #111114;
  --rule-soft: #c8c3b3;
  --accent: #1f4d3a;           /* 모스 그린 — 옛 의학 도서관 표지의 색 */
  --accent-light: #2f6b51;
  --highlight: #f0e5b8;
  --crimson: #7a2419;          /* 보조 강조, 매우 제한적 사용 */

  /* Status colors */
  --status-recruiting: #2f6b51;
  --status-active: #1f4276;
  --status-completed: #5a2818;
  --status-terminated: #6c6c70;

  /* Typography */
  --font-display: 'Noto Serif KR', Georgia, 'Times New Roman', serif;
  --font-body: 'Noto Serif KR', Georgia, 'Times New Roman', serif;
  --font-sans: 'Pretendard Variable', 'Pretendard', -apple-system, BlinkMacSystemFont, 'Segoe UI', sans-serif;
  --font-mono: 'JetBrains Mono', 'D2Coding', 'Courier New', monospace;

  /* Layout */
  --max-width: 1240px;
  --measure: 64ch;
}

* { box-sizing: border-box; margin: 0; padding: 0; }

html { font-size: 17px; scroll-behavior: smooth; }

body {
  font-family: var(--font-body);
  font-feature-settings: "kern" 1, "liga" 1;
  background: var(--paper);
  color: var(--ink);
  line-height: 1.75;
  word-break: keep-all;
  overflow-wrap: break-word;
  text-rendering: optimizeLegibility;
  -webkit-font-smoothing: antialiased;
}

/* ==========================================================================
   Masthead — 연구소 명함 같은 절제된 헤더
   ========================================================================== */
.masthead {
  border-bottom: 1px solid var(--rule);
  background: var(--paper);
  padding: 1.5rem 0 1.25rem;
}

.masthead-inner {
  max-width: var(--max-width);
  margin: 0 auto;
  padding: 0 2.5rem;
  display: grid;
  grid-template-columns: auto 1fr auto;
  align-items: center;
  gap: 2rem;
}

/* 모노그램 — DYPHI FLC */
.monogram {
  display: flex;
  align-items: center;
  gap: 0.85rem;
}

.monogram-mark {
  width: 44px;
  height: 44px;
  border: 1.5px solid var(--ink);
  display: flex;
  align-items: center;
  justify-content: center;
  font-family: var(--font-sans);
  font-weight: 700;
  font-size: 0.88rem;
  letter-spacing: 0.04em;
  background: var(--ink);
  color: var(--paper);
}

.monogram-text {
  display: flex;
  flex-direction: column;
  line-height: 1.05;
}

.monogram-org {
  font-family: var(--font-sans);
  font-size: 0.7rem;
  font-weight: 500;
  text-transform: uppercase;
  letter-spacing: 0.18em;
  color: var(--ink-mute);
}

.monogram-name {
  font-family: var(--font-display);
  font-weight: 600;
  font-size: 1.18rem;
  letter-spacing: -0.01em;
  color: var(--ink);
  text-decoration: none;
  margin-top: 2px;
}

.monogram-name:hover { color: var(--accent); }

.masthead-tagline {
  font-family: var(--font-sans);
  font-size: 0.88rem;
  font-weight: 400;
  color: var(--ink-mute);
  text-align: center;
  letter-spacing: 0.02em;
}

.masthead-meta {
  font-family: var(--font-mono);
  font-size: 0.7rem;
  text-transform: uppercase;
  letter-spacing: 0.12em;
  color: var(--ink-mute);
  text-align: right;
  line-height: 1.5;
}

@media (max-width: 880px) {
  .masthead-inner {
    grid-template-columns: 1fr;
    text-align: left;
    gap: 0.75rem;
  }
  .masthead-tagline, .masthead-meta { text-align: left; }
}

/* ==========================================================================
   Navigation
   ========================================================================== */
.nav-bar {
  border-bottom: 1px solid var(--rule);
  background: var(--paper);
  position: sticky;
  top: 0;
  z-index: 10;
}

.nav-inner {
  max-width: var(--max-width);
  margin: 0 auto;
  padding: 0 2.5rem;
  display: flex;
  overflow-x: auto;
}

.nav-inner a {
  font-family: var(--font-sans);
  font-size: 0.78rem;
  font-weight: 500;
  text-transform: uppercase;
  letter-spacing: 0.12em;
  color: var(--ink-mute);
  text-decoration: none;
  padding: 1rem 1.5rem 1rem 0;
  margin-right: 2rem;
  transition: color 0.15s;
  white-space: nowrap;
  border-bottom: 2px solid transparent;
  position: relative;
  top: 1px;
}

.nav-inner a:hover { color: var(--ink); }
.nav-inner a.active {
  color: var(--ink);
  border-bottom-color: var(--accent);
}

/* ==========================================================================
   Layout
   ========================================================================== */
.container {
  max-width: var(--max-width);
  margin: 0 auto;
  padding: 3.5rem 2.5rem 5rem;
}

.container-narrow {
  max-width: 760px;
  margin: 0 auto;
  padding: 3.5rem 2.5rem 5rem;
}

/* ==========================================================================
   Typography
   ========================================================================== */
h1, h2, h3, h4 {
  font-family: var(--font-display);
  font-weight: 600;
  letter-spacing: -0.01em;
  color: var(--ink);
  line-height: 1.25;
  word-break: keep-all;
}

h1 {
  font-size: 2.5rem;
  font-weight: 700;
  margin-bottom: 0.6rem;
  line-height: 1.15;
}

h2 {
  font-size: 1.55rem;
  margin: 2.5rem 0 1rem;
  padding-bottom: 0.5rem;
  border-bottom: 1px solid var(--rule-soft);
}

h3 {
  font-size: 1.18rem;
  margin: 1.8rem 0 0.6rem;
  font-weight: 600;
}

h4 {
  font-size: 1rem;
  margin: 1.2rem 0 0.5rem;
  font-weight: 600;
}

p { margin-bottom: 1rem; max-width: var(--measure); }

p.lead {
  font-size: 1.12rem;
  line-height: 1.7;
  color: var(--ink-soft);
  font-style: italic;
  margin-bottom: 2rem;
}

a {
  color: var(--accent);
  text-decoration: underline;
  text-decoration-thickness: 1px;
  text-underline-offset: 3px;
  text-decoration-color: var(--rule-soft);
  transition: text-decoration-color 0.15s, color 0.15s;
}

a:hover {
  color: var(--accent-light);
  text-decoration-color: var(--accent);
}

ul, ol { margin: 1rem 0 1rem 1.5rem; max-width: var(--measure); }
li { margin-bottom: 0.4rem; }

code {
  font-family: var(--font-mono);
  font-size: 0.85em;
  background: var(--paper-warm);
  padding: 0.1em 0.4em;
  border-radius: 2px;
}

blockquote {
  border-left: 2px solid var(--accent);
  padding: 0.4rem 1.3rem;
  margin: 1.5rem 0;
  font-style: italic;
  color: var(--ink-soft);
}

/* ==========================================================================
   Hero — center 홈
   ========================================================================== */
.hero {
  padding: 5rem 0 4rem;
  border-bottom: 1px solid var(--rule);
  margin-bottom: 4rem;
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 4rem;
  align-items: end;
}

.hero-eyebrow {
  font-family: var(--font-mono);
  font-size: 0.72rem;
  text-transform: uppercase;
  letter-spacing: 0.18em;
  color: var(--accent);
  margin-bottom: 1.5rem;
}

.hero-title {
  font-family: var(--font-display);
  font-size: clamp(2.2rem, 4.5vw, 3.4rem);
  font-weight: 700;
  line-height: 1.1;
  letter-spacing: -0.02em;
  margin-bottom: 0;
  word-break: keep-all;
}

.hero-title em {
  font-style: italic;
  color: var(--accent);
  font-weight: 500;
}

.hero-desc {
  font-family: var(--font-sans);
  font-size: 1rem;
  font-weight: 400;
  color: var(--ink-soft);
  line-height: 1.75;
}

.hero-desc p { margin-bottom: 0.8rem; max-width: 50ch; }

@media (max-width: 880px) {
  .hero {
    grid-template-columns: 1fr;
    gap: 1.5rem;
    padding: 3rem 0 2.5rem;
  }
}

/* ==========================================================================
   Section labels — 콘텐츠 유형 구분
   ========================================================================== */
.section-block {
  margin-bottom: 4rem;
}

.section-header {
  display: grid;
  grid-template-columns: 220px 1fr;
  gap: 3rem;
  border-top: 1px solid var(--rule);
  padding-top: 1.5rem;
  margin-bottom: 1.5rem;
}

.section-header-label {
  font-family: var(--font-mono);
  font-size: 0.72rem;
  text-transform: uppercase;
  letter-spacing: 0.15em;
  color: var(--ink-mute);
  padding-top: 0.6rem;
}

.section-header-label .num {
  display: block;
  font-family: var(--font-display);
  font-weight: 600;
  font-size: 1.4rem;
  color: var(--ink);
  font-style: italic;
  margin-top: 0.2rem;
}

.section-header-content h2 {
  border-bottom: none;
  margin: 0 0 0.4rem;
  padding: 0;
  font-size: 1.7rem;
  font-weight: 600;
}

.section-header-content p {
  color: var(--ink-soft);
  font-size: 1rem;
  margin: 0;
}

@media (max-width: 720px) {
  .section-header {
    grid-template-columns: 1fr;
    gap: 0.5rem;
  }
}

/* ==========================================================================
   Item card — Clinical / Research / Policy 공통
   ========================================================================== */
.item-list {
  border-top: 1px solid var(--rule-soft);
}

.item-card {
  display: grid;
  grid-template-columns: 110px 1fr 120px;
  gap: 2rem;
  padding: 1.6rem 0;
  border-bottom: 1px solid var(--rule-soft);
  align-items: baseline;
  text-decoration: none;
  color: inherit;
  transition: padding-left 0.18s ease, background 0.15s;
}

.item-card:hover {
  padding-left: 0.6rem;
  background: linear-gradient(to right, var(--paper-warm) 0%, transparent 80%);
  text-decoration: none;
}

.item-card:hover .item-title {
  color: var(--accent);
  text-decoration-color: var(--accent);
}

.item-date {
  font-family: var(--font-mono);
  font-size: 0.78rem;
  color: var(--ink-mute);
  letter-spacing: 0.05em;
  white-space: nowrap;
  padding-top: 0.15rem;
}

.item-body { min-width: 0; }

.item-kind {
  font-family: var(--font-mono);
  font-size: 0.65rem;
  text-transform: uppercase;
  letter-spacing: 0.15em;
  color: var(--ink-mute);
  margin-bottom: 0.4rem;
}

.item-kind.clinical { color: var(--accent); }
.item-kind.regenbrief { color: var(--ink); }
.item-kind.policy { color: var(--crimson); }

.item-title {
  font-family: var(--font-display);
  font-weight: 600;
  font-size: 1.2rem;
  line-height: 1.35;
  margin-bottom: 0.5rem;
  letter-spacing: -0.01em;
  color: var(--ink);
  word-break: keep-all;
  transition: color 0.15s;
}

.item-summary {
  font-family: var(--font-sans);
  font-size: 0.92rem;
  font-weight: 400;
  color: var(--ink-soft);
  line-height: 1.65;
  max-width: 60ch;
  word-break: keep-all;
}

.item-meta {
  display: flex;
  flex-wrap: wrap;
  gap: 0.4rem;
  margin-top: 0.7rem;
  align-items: center;
}

.tag {
  display: inline-block;
  font-family: var(--font-mono);
  font-size: 0.66rem;
  text-transform: uppercase;
  letter-spacing: 0.08em;
  padding: 0.18rem 0.55rem;
  border: 1px solid var(--rule-soft);
  background: transparent;
  color: var(--ink-soft);
  border-radius: 1px;
}

.tag-phase {
  background: var(--ink);
  color: var(--paper);
  border-color: var(--ink);
  font-weight: 500;
}

.tag-source { background: var(--paper-warm); }

.item-status {
  font-family: var(--font-mono);
  font-size: 0.65rem;
  text-transform: uppercase;
  letter-spacing: 0.12em;
  white-space: nowrap;
  padding: 0.25rem 0.7rem;
  border-radius: 1px;
  color: var(--paper);
  align-self: start;
  margin-top: 0.2rem;
  text-align: center;
}

.status-recruiting { background: var(--status-recruiting); }
.status-active { background: var(--status-active); }
.status-completed { background: var(--status-completed); }
.status-terminated { background: var(--status-terminated); }
.status-draft {
  background: transparent;
  color: var(--ink-mute);
  border: 1px solid var(--rule-soft);
}

@media (max-width: 720px) {
  .item-card {
    grid-template-columns: 1fr;
    gap: 0.4rem;
  }
  .item-status { justify-self: start; margin-top: 0.5rem; }
}

/* ==========================================================================
   Stats panel — 절제된 숫자 표시
   ========================================================================== */
.stats-panel {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(160px, 1fr));
  gap: 0;
  border-top: 1px solid var(--rule);
  border-bottom: 1px solid var(--rule);
  margin: 0 0 4rem;
}

.stat {
  padding: 1.5rem 1.5rem 1.5rem 0;
  border-right: 1px solid var(--rule-soft);
}

.stat:last-child { border-right: none; }

.stat-num {
  font-family: var(--font-display);
  font-size: 2.6rem;
  font-weight: 700;
  line-height: 1;
  color: var(--ink);
  letter-spacing: -0.02em;
}

.stat-num em {
  font-style: italic;
  color: var(--accent);
  font-weight: 400;
}

.stat-label {
  font-family: var(--font-mono);
  font-size: 0.7rem;
  text-transform: uppercase;
  letter-spacing: 0.12em;
  color: var(--ink-mute);
  margin-top: 0.5rem;
}

/* ==========================================================================
   Detail page — clinical / research / policy 상세
   ========================================================================== */
.detail-header {
  border-bottom: 1px solid var(--rule);
  padding-bottom: 2rem;
  margin-bottom: 2.5rem;
}

.detail-eyebrow {
  font-family: var(--font-mono);
  font-size: 0.72rem;
  text-transform: uppercase;
  letter-spacing: 0.15em;
  color: var(--accent);
  margin-bottom: 1.2rem;
}

.detail-meta-table {
  margin: 2rem 0;
  font-size: 0.92rem;
  width: 100%;
  border-collapse: collapse;
  border-top: 1px solid var(--rule);
  border-bottom: 1px solid var(--rule);
}

.detail-meta-table tr { border-bottom: 1px solid var(--rule-soft); }
.detail-meta-table tr:last-child { border-bottom: none; }

.detail-meta-table th {
  text-align: left;
  padding: 0.7rem 1.5rem 0.7rem 0;
  font-family: var(--font-mono);
  font-size: 0.7rem;
  text-transform: uppercase;
  letter-spacing: 0.12em;
  font-weight: 500;
  color: var(--ink-mute);
  width: 30%;
  vertical-align: top;
}

.detail-meta-table td {
  padding: 0.7rem 0;
  vertical-align: top;
  font-family: var(--font-sans);
  font-size: 0.95rem;
}

/* ==========================================================================
   Index page (적응증/세포원/단계별)
   ========================================================================== */
.index-section {
  margin-bottom: 3.5rem;
}

.index-section-header {
  display: flex;
  align-items: baseline;
  gap: 1rem;
  border-bottom: 2px solid var(--rule);
  padding-bottom: 0.6rem;
  margin-bottom: 1rem;
}

.index-section-header h2 {
  border-bottom: none;
  margin: 0;
  padding: 0;
  font-size: 1.5rem;
}

.index-section-header .count {
  font-family: var(--font-mono);
  font-size: 0.78rem;
  color: var(--ink-mute);
  letter-spacing: 0.05em;
}

.index-subhead {
  font-family: var(--font-display);
  font-style: italic;
  font-size: 1.1rem;
  margin-top: 1.5rem;
  margin-bottom: 0.4rem;
  color: var(--ink);
}

.index-subhead small {
  font-family: var(--font-mono);
  font-size: 0.72rem;
  color: var(--ink-mute);
  font-style: normal;
  margin-left: 0.5rem;
  letter-spacing: 0.05em;
}

/* ==========================================================================
   Footer
   ========================================================================== */
.site-footer {
  border-top: 1px solid var(--rule);
  padding: 3rem 0 2.5rem;
  margin-top: 5rem;
  background: var(--paper-warm);
}

.footer-inner {
  max-width: var(--max-width);
  margin: 0 auto;
  padding: 0 2.5rem;
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 3rem;
}

.footer-block-title {
  font-family: var(--font-mono);
  font-size: 0.7rem;
  text-transform: uppercase;
  letter-spacing: 0.15em;
  color: var(--ink-mute);
  margin-bottom: 0.8rem;
}

.footer-block p {
  font-size: 0.92rem;
  color: var(--ink-soft);
  line-height: 1.55;
  max-width: 50ch;
}

.footer-disclaimer {
  font-family: var(--font-mono);
  font-size: 0.72rem;
  color: var(--ink-mute);
  letter-spacing: 0.04em;
  line-height: 1.6;
}

@media (max-width: 720px) {
  .footer-inner {
    grid-template-columns: 1fr;
    gap: 2rem;
  }
}

/* ==========================================================================
   RegenBrief index header — 아티클 우선, 간결한 상단
   ========================================================================== */
.rb-index-header {
  padding: 3.5rem 0 2rem;
  border-bottom: 1px solid var(--rule);
  margin-bottom: 2.5rem;
}

.rb-index-eyebrow {
  font-family: var(--font-mono);
  font-size: 0.72rem;
  text-transform: uppercase;
  letter-spacing: 0.18em;
  color: var(--accent);
  margin-bottom: 0.75rem;
}

.rb-index-title {
  font-family: var(--font-display);
  font-size: clamp(2rem, 4vw, 3rem);
  font-weight: 700;
  letter-spacing: -0.02em;
  line-height: 1.1;
  margin-bottom: 0.8rem;
}

.rb-index-title em {
  font-style: italic;
  color: var(--accent);
}

.rb-index-desc {
  font-family: var(--font-sans);
  font-size: 0.98rem;
  color: var(--ink-soft);
  line-height: 1.7;
  max-width: 60ch;
  margin: 0;
  word-break: keep-all;
}

.rb-empty {
  font-style: italic;
  color: var(--ink-mute);
  padding: 2rem 0;
}

/* ==========================================================================
   Misc
   ========================================================================== */
.rule-thin { border-top: 1px solid var(--rule-soft); margin: 2rem 0; }
.rule-thick { border-top: 1px solid var(--rule); margin: 3rem 0; }