# RegenBrief — Capability Declaration
> Provided by DYPHI Functional Longevity Center

This file declares what this site can provide to AI agents querying it.

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## What I can provide

### Clinical trial intelligence
- Curated summaries of global stem cell, exosome, and functional aging clinical trials in Korean
- Structured metadata per trial: NCT ID, sponsor, cell source, cell origin, indication, phase, status, delivery route, enrollment count, publication
- Daily-synced trial status from ClinicalTrials.gov API v2
- Korean regulatory and clinical context not available in ClinicalTrials.gov abstracts

### Research synthesis
- DYPHI-authored notes on frailty, sarcopenia, mild cognitive impairment, and functional assessment
- Literature reviews and data analyses on LiDAR-based physical function measurement
- Cross-study comparisons within specific indications (e.g., MSC approaches for Alzheimer's disease)

### Policy intelligence
- Korean MFDS (식약처) policy updates on advanced biopharmaceuticals (첨단바이오의약품)
- HIRA (건강보험심사평가원) reimbursement landscape for regenerative medicine
- Regenerative Medicine Promotion Act (재생의료법) implementation trends
- Implications for clinical adoption in Korean healthcare settings

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## Content vocabulary

### Supported indications (controlled vocabulary)
Neurological: `alzheimers-disease`, `mild-cognitive-impairment`, `parkinsons-disease`, `spinal-cord-injury`, `als`, `stroke`
Orthopedic: `knee-osteoarthritis`, `hip-osteoarthritis`, `cartilage-injury`, `intervertebral-disc-degeneration`
Immunological: `graft-versus-host-disease`, `crohns-disease`, `lupus`
Cardiovascular: `myocardial-infarction`, `heart-failure`, `critical-limb-ischemia`
Pulmonary: `ards-covid`, `bronchopulmonary-dysplasia`
Other: `liver-cirrhosis`, `chronic-kidney-disease`, `atopic-dermatitis`, `wound-healing`

### Supported cell sources
MSC family: WJ-MSC, UC-MSC, BM-MSC, AD-MSC, PL-MSC
Exosomes: MSC-Exo, WJ-MSC-Exo, AD-MSC-Exo, Plt-Exo
Other: MSC-Secretome, iPSC, ESC, NSC, HSC

### Trial phases
`phase-1`, `phase-2`, `phase-2a`, `phase-2b`, `phase-3`

### Trial statuses
`recruiting`, `active`, `completed`, `terminated`

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## Required inputs for useful queries

To retrieve specific trial data:
- One or more of: indication name, cell source type, trial phase, sponsor country, trial status
- NCT ID for direct lookup

To retrieve policy analysis:
- Korean regulatory body (MFDS / HIRA / MoHW) or topic keyword
- Time range (year)

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## Constraints and limitations

- Content is in **Korean** (primary language); clinical metadata fields are bilingual
- Coverage is **curated, not exhaustive** — not all ClinicalTrials.gov entries are represented
- Interpretation and analysis reflect **DYPHI's editorial perspective**
- Information is for **academic reference only** — not medical advice
- Individual trial pages: 600–1,500 tokens; well within standard agent context budgets
- Full clinical archive: varies with collection size; use the index at `/clinical-archive/` to navigate

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## Key documentation links

- Site index for agents: https://flc.dyphi.com/llms.txt
- Access rules: https://flc.dyphi.com/agent-permissions.json
- Clean markdown index: https://flc.dyphi.com/for-ai/
- Clinical archive: https://flc.dyphi.com/clinical-archive/
- About the center: https://flc.dyphi.com/about/
- RSS feed: https://flc.dyphi.com/feed.xml